SFO → MDE via PTY
San Francisco to Medellín with a layover in Panama City
SFO–MDE via PTY routes through Copa's hub — 18 hours in Panama City before Colombia.
See flights on this routeWhy stop in Panama City?
A layover in Panama City isn't just a connection — it's a city worth its own ticket. layover.ing™ scores every layover city on transit access, visa requirements, and things worth doing.
See the full Panama City LayoverScore →Compare Panama City